Molecular pathogenesis of human CD59 deficiency

The Molecular Pathogenesis of Human Prostate Cancer

Pathogenesis of creatine transporter deficiency

Molecular basis of glutathione reductase deficiency in human blood cells Short title: Human glutathione reductase deficiency

NMK performed research, collected and analyzed data and wrote the paper; RvZ collected patient material, performed research and analyzed data; MdB performed sequence analysis and analyzed data; GM performed sequence analysis; HV performed patient RBC analysis; NB treated one patient and collected data; CL treated one patient, collected data and wrote a clinical report; KMD interviewed three pat...

Molecular pathogenesis and therapeutic strategies of human osteosarcoma

Osteosarcoma (OS) is a devastating illness with rapid rates of dissemination and a poor overall prognosis, despite aggressive standard-of-care surgical techniques and combination chemotherapy regimens. Identifying the molecular mechanisms involved in disease pathogenesis and progression may offer insight into new therapeutic targets. Defects in mesenchymal stem cell differentiation, abnormal ex...

Molecular aspects in the pathogenesis of human systemic lupus erythematosus.

Systemic lupus erythematosus is a common and often devastating systemic autoimmune disease of unknown etiology. In this communication we review the latest developments of the molecular pathogenesis of human lupus. Novel genetic studies of multiplex lupus families have revealed potential disease-associated genome intervals, put special emphasis on genetic loci mapping in the long arm of chromoso...